Destroyer
The destroyer is a master of weapons, if you don’t have 3+ “situational” weapons in your warehouse or on your person, you simply aren’t playing the class to its fullest. Majestic heavy is good with +STR, doom heavy +6 works well with +CON. Blue wolf heavy +6 would help you to catch up with slower targets in PvP
Tyrant
Tallum heavy and blood tornado with Focus worked very well in C3. I have seen a lot more tyrants recently in light armors instead of heavy, especially nightmare light with dragon grinders, most likely with the health SA. It also doesn’t hurt to have another set of fist weapons for PvP with some sort of risk SA on them, for when your hp drops below 30%.
+STR : more damage.
+DEX : faster attack speed.
+CON : more HP for PvP, but get a health SA as well