You can add some cool things like:
Make these buffs on items, an item that will give you the stats that you mention and add em on an NPC called "The Dealer" or name the buffer that will give these buffs with that name if you do not make em on an item.
Make a debuff for raids called "Heroin", this debuff will decrease speed, atk spd and casting spd by 5% for example (you got my point).
and use your imagination to find more and more ;p to create something new, don't get your base only on drugs but generally on things we're gonna see in real life, like drinks, drugs, etc